Cancer Prevention II

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Breast Cancer Screening and Diagnosis. Ann Epidemiol. Back to top Article Information. So those sorts of model systems are very important. The most prevalent type of lung cancer, non-small cell lung cancer, has four stages. Cancer incidence follow-up is being conducted in The CPS II Nutrition cohort, a subgroup of , men and women who completed a second questionnaire in

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However, an additional 2. Percentages are among those with non-missing data see Table 1 for completeness of data. Figure 3 shows the sex-specific trends in vascular risk factors either by birth cohort or by age.

The most notable secular trends were in smoking habits and alcohol use. Very few women reportedly smoked in any birth cohort. The prevalence of obesity was low overall, and was slightly higher in younger than older men, but lower in younger than older women. Major vascular risk factors by year of birth or age at recruitment. A Prevalence of smoking and drinking in men, by birth cohort. B Prevalence of smoking and drinking in women, by birth cohort. E Mean systolic and diastolic blood pressure in men and women, by age at recruitment. KCPS-II Biobank data, or subsets of the data, have already been used in several epidemiological 9 , 10 and genetic studies, 11—14 and have contributed to international collaborative research projects.

As the cohort continues to mature, further analyses exploring the importance to health of a range of lifestyle and biological characteristics will be performed. This will include studying not only the metabolic syndrome and other traditional vascular and neoplastic risk factors, but also genetic factors as well as a wide range of other factors measurable in blood e.

The main strengths of this study are its size, its reliable and detailed linkage to health records and its collection of blood samples at recruitment in all participants. A feature of the study population is its relatively young age the average baseline age was 42 years , meaning it will be able to evaluate the long-term effects of health behaviours and habits in early middle age.

However, this does also mean that it will be some time until sufficient numbers of major health events such as vascular disease or cancer occur before reliable statistical analyses can be done. Some collected information in particular on socioeconomic status and pulmonary function was limited to just a few centres, so analyses that require such measures will only be possible in a subset of the overall cohort. In addition, the cohort is not representative of the entire South Korean population, as study participants were recruited mainly from the Seoul and Gyeonggi regions.

It will not, therefore, necessarily provide generalizable estimates of the prevalences of particular characteristics. However, by including a large number of people who differ according to their lifestyles, their biological and their genetic characteristics, the study is very well placed to deliver on its main aim of studying the associations between genetic or environmental risk factors and future disease incidence.

The KCPS-II Biobank data are not freely available, but the study group has collaborated with several other groups to share study data and encourage new collaborations. Potential collaborators are invited to contact the Secretary General S.

Who is in the cohort?

The Cancer Prevention Study II (CPS-II), which began in , is a prospective mortality study of approximately million American men and women. CPS-II Nutrition Survey. New questionnaires were sent to the CPS-II Nutrition Survey cohort in , , , , , Stat Bull Metrop Insur Co. Oct-Dec;73(4) Cancer Prevention Study II. The American Cancer Society Prospective Study. [No authors listed]. Over the.

Mean age at recruitment was 42 years. The health assessment involved self-completion of a questionnaire which contained questions about health status and associated behaviours; attenders then took part in a medical examination during which weight, height, waist circumference and blood pressure were measured.

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Serum was also used for immediate biomarker analysis. The authors wish to thank the Korean Central Cancer Registry and the National Insurance Data Service for their assistance in disease and mortality data linkage. Moreover, we would also like to thank the study participants who agreed to provide their data. Conflict of interest: The authors declare that they have no competing interests. Oxford University Press is a department of the University of Oxford. It furthers the University's objective of excellence in research, scholarship, and education by publishing worldwide.

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Sign In. Advanced Search. Article Navigation. Close mobile search navigation Article Navigation. Volume Article Contents. Why was the cohort set up? Who is in the cohort?

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What has been measured? How often have they been followed up? What has it found? Key findings and publications. What are the main strengths and weaknesses? Can I get hold of the data? These questionnaires updated information on exposures and also captured self-reported cancer incidence. Ongoing cancer incidence follow-up for the CPS-II Nutrition Survey cohort is conducted by validating self-reported incidence cancers using medical records or linkage with state cancer registries. Nearly 30, incident cancers were reported in the interval to These data are used to examine the association of many factors e.

Mortality follow-up of the entire CPS-II Nutrition Survey cohort will allow the study of the association between reported risk factors and survival. Initial findings include marked associations between obesity and aggressive forms of prostate cancer.